The FOCU.SE trial: a nationwide Swedish drug repurposing protocol and research framework

Edvard Abel; Päivi Östling; Ebba Hallersjö Hult; Katarzyna Kulbacka; Haris Babacic; Annika Baan; Ana Carneiro; Luigi De Petris; Henrik Fagman; Signe Friesland; Oskar Frisell; Mats Hellström; Gabriel Lindahl; Katarina Steen Carlsson; David Tamborero; Antonios Valachis; Daniel Öhlund; Janne Lehtiö; Richard Rosenquist; Anders Edsjö; Johan Botling; Helena Bäckvall; Rikard Fred; Stina Garvin; Andreas Hallqvist; Markus Heidenblad; Tina Catela-Ivkovic; Anita Koskela von Sydow; Linda Köhn; Rozina Caridha Lagerhorn; Maja Löfgren; Malin Melin; Martin Isaksson-Mettävainio; Lotte NJ Moens; Lars Ny; Helena Nord; Hannes Olauson; Alvida Qvick; Stefano Rapisarda; Emma Tham; FOCU.SE trial group

doi:10.2340/ao.v65.45355

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The FOCU.SE trial: a nationwide Swedish drug repurposing protocol and research framework

Letter/Communication

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The FOCU.SE trial: a nationwide Swedish drug repurposing protocol and research framework

Edvard Abel, Päivi Östling, Ebba Hallersjö Hult, Katarzyna Kulbacka, Haris Babacic, Annika Baan, Ana Carneiro, Luigi De Petris, Henrik Fagman, Signe Friesland, …

Acta Oncologica, Vol.65, p.268

2026-04-13

DOI: https://doi.org/10.2340/ao.v65.45355

PMID: 41972845

Abstract

Precision medicine

biomarker profiling

drug repurposing

targeted therapy

platform trial

multimodal analysis

PRIMEROSE consortium

cancer genomics

Infrastructure

Proteomics

Sweden

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Title: The FOCU.SE trial: a nationwide Swedish drug repurposing protocol and research framework
Creators: Edvard Abel - University of Gothenburg
Päivi Östling - Karolinska University Hospital
Ebba Hallersjö Hult - Stockholm School of Economics, SSE Institute for Research
Katarzyna Kulbacka - Sahlgrenska University Hospital
Haris Babacic - Karolinska Institutet
Annika Baan - Sahlgrenska University Hospital
Ana Carneiro - Lund University
Luigi De Petris - Karolinska University Hospital
Henrik Fagman - University of Gothenburg
Signe Friesland - Karolinska Institutet
Oskar Frisell - Swedish Institute for Health Economics
Mats Hellström - Uppsala University
Gabriel Lindahl - Linköping University
Katarina Steen Carlsson - Swedish Institute for Health Economics
David Tamborero - Karolinska Institutet
Antonios Valachis - Örebro University
Daniel Öhlund - Umeå University
Janne Lehtiö - Karolinska Institutet
Richard Rosenquist - Karolinska Institutet
Anders Edsjö - Skåne University Hospital
Johan Botling - University of Gothenburg
Helena Bäckvall - Karolinska Institutet
Rikard Fred - Karolinska Institutet
Stina Garvin - Region Östergötland
Andreas Hallqvist - University of Gothenburg
Markus Heidenblad - Lund University
Tina Catela-Ivkovic - Lund University
Anita Koskela von Sydow - Örebro University
Linda Köhn - Umeå University
Rozina Caridha Lagerhorn - Karolinska Institutet
Maja Löfgren - Sahlgrenska University Hospital
Malin Melin - Uppsala University
Martin Isaksson-Mettävainio - Umeå University
Lotte NJ Moens - Uppsala University Hospital
Lars Ny - University of Gothenburg
Helena Nord - Uppsala University Hospital
Hannes Olauson - Karolinska University Hospital
Alvida Qvick - Örebro University
Stefano Rapisarda - Karolinska Institutet
Emma Tham - Karolinska Institutet
FOCU.SE trial group
Publication Details: Acta Oncologica, Vol.65, p.268
Publisher: MJS Publishing
Copyright: © 2026 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Inter-national License (http://creativecommons.org/licenses/by/4.0/)
Academic Unit: SSE Institute for Research
Language: English
Resource Type: Letter/Communication

The FOCU.SE trial: a nationwide Swedish drug repurposing protocol and research framework

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